RhoC, vascular endothelial growth factor and microvascular density in esophageal squamous cell carcinoma

Table 1 Ras homolog C mRNA relative content, expression of Ras homolog C mRNA and protein and vascular endothelial growth factor protein in normal esophageal mucosa, adjacent atypical hyperplasia, and cancer tissues

Site	Cases (n)	RhoC mRNA relative content	χ2	P value	RhoC mRNA expression			χ2	P value	RhoC protein expression			χ2	P value	VEGF protein expression			χ2	P value
					-	+	Positive rate			-	+	Positive rate			-	+	Positive rate
Normal esophageal mucosa tissues	62	0.653 ± 0.069			49	13	21%			50	12	19.4%			44	18	29%
Adjacent atypical hyperplasia tissues	31	0.731 ± 0.065	99.629	0.000	21	10	32.3%	47.735	0.000	20	11	35.5%	54.25	0.000	14	17	54.8%	18.994	0.000
Cancer tissues	62	0.902 ± 0.119			12	50	80.6%			10	52	83.9%			20	42	67.7%

RhoC: Ras homolog C; VEGF: Vascular endothelial growth factor.