Allocation of patients with liver cirrhosis and organ failure to intensive care: Systematic review and a proposal for clinical practice

Table 5 Chronic Liver Failure-Sequential Organ Failure Assessment score

Organ	Variabel	0	1	2	3	4
Liver	Billirubin, μmol/L	< 20 μmol/L	≥ 20 to < 34 μmol/L	≥ 34 to < 103 μmol/L	≥ 103 to < 205 μmol/L	> 205 μmol/L
	(mg/dL)	(-1.1)	(≥ 1.1 to < 1.9 )	(≥ 1.9 to < 6.0)	(≥ 6.0 to < 11.9)	(> 11.9)1
Kidney	Creatinine, μmol/L	< 106 μmol/L	≥ 106 to < 177 μmol/L	≥ 177 to < 309 μmol/L	≥ 309 to < 442 μmol/L	> 442 μmol/L
	(mg/dL)	(< 1.2)	(≥ 1.2 to < 2.0)	(≥ 1.2 to < 3.5)1	(≥ 3.5 to < 5)1	(> 5.0)1
				Or renal replacement therapy1
CNS	HE grade	None	I	II	III1	IV1
Coagulation	INR	< 1.1	≥ 1.1 to 1.25	≥ 1.25 to < 1.5	≥ 1.5 to < 2.5	≥ 2.5 or platlets < 201
Circulation	MAP (mmHg)	≥ 70	< 70	Dopamine ≤ 51	Dopamine > 51	Dopamine > 15
				Dobutamine	Epinephrine ≤ 0.11	Epinephrine > 0.1
				Terlipressin1	Norepinephrine ≤ 0.11	Norepinephrine > 0.11
Lungs	PaO2/FiO2	> 400	> 300 to ≤ 400	> 200 to ≤ 300	> 100 to ≤ 2001	≤ 1001
	SpO2/FiO2	> 512	> 357 to ≤ 512	> 214 to < 357	> 89 to ≤ 2141	≤ 891

¹Indicates the limit for the definition of organ failure. HE: Hepatic encephalopathy; MAP: Mean arterial pressure; PaO₂: Arterial oxygen tension; FiO₂: Fraction of inspired oxygen; SpO₂: Peripheral capillary oxygen saturation.