Serum proinflammatory cytokines and nutritional status in pediatric chronic liver disease

Table 1 Demographic and clinical data of the study population n (%)

Variables	Patients (n = 43)
Age (yr)
< 2	13 (30.2)
2-5	9 (20.9)
5-10	11 (25.6)
> 10	10 (23.3)
Female	23 (53.5)
Nutritional status1
Well-nourished	28 (65.1)
Risk of malnutrition	10 (23.3)
Malnutrition	5 (11.6)
Causes of chronic liver disease
Biliary atresia	31 (72)
Alpha-1 antitrypsin deficiency	6 (14)
Sinusoidal obstruction syndrome	1 (2.3)
Idiopathic chronic liver disease	1 (2.3)
Cirrhosis by cytomegalovirus	1 (2.3)
Cryptogenic cirrhosis	3 (7)
Cholestasis (CB ≥ 2.0 mg/dL)	12 (27.9)
Albumin (< 3.5 g/L)	12 (27.9)
Portal hypertension	24 (55.8)
Ascites	3 (7)
Hepatomegaly	25 (58.1)
Splenomegaly	32 (74.4)
Cirrhosis	35 (81.4)
Child-Pugh score
A	20/35 (57.1)
B	12/35 (34.3)
C	3/35 (8.6)
PELD score (> 15)	4/27 (14.8)
MELD score (> 15)	1/8 (12.5)

¹Parameters for nutritional assessment: triceps skinfold-for-age and body mass index-for-age. CB: Conjugated bilirubin; PELD: Pediatric end stage liver disease; MELD: Model for end stage liver disease.