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©The Author(s) 2015.
World J Gastroenterol. Jul 28, 2015; 21(28): 8653-8659
Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8653
Published online Jul 28, 2015. doi: 10.3748/wjg.v21.i28.8653
Table 1 Characteristics of chronic hepatitis B patients with or with no virological relapse n (%)
| Factors | Virological relapse (n = 162) | No virological relapse (n = 42) | P value |
| Age (yr) | 36.83 ± 10.51 | 35.19 ± 9.10 | 0.357 |
| Gender | |||
| Male | 95 (58.64) | 26 (61.9) | 0.332 |
| Female | 67 (41.36) | 16 (38.1) | |
| Vertical transmission of infection history | |||
| Yes | 80 (49.38) | 21 (50) | 0.936 |
| No | 82 (50.62) | 21 (50) | |
| Time to undetectable HBV DNA | 5.01 ± 2.11 | 4.93 ± 2.96 | 0.819 |
| Sustained time of antiviral | 44.62 ± 8.17 | 41.21 ± 6.20 | 0.110 |
| Drugs used | |||
| Lamivudine | 29 (17.9) | 10 (23.81) | 0.736 |
| Adefovir | 36 (22.22) | 11 (26.19) | |
| Telbivudine | 25 (12.35) | 4 (9.52) | |
| Entecavir | 44 (27.16) | 10 (23.81) | |
| Lamivudine + Adefovir | 28 (17.28) | 7 (16.67) | |
| Follow-up time of cessation, mo | 8.99 ± 9.38 | 25.71 ± 2.17 | < 0.0001 |
| Level of HBsAg at the end of therapy (IU/L) | 4334.179 ± 2493.99 | 3290.163 ± 2019.79 | 0.013 |
| Genotype | |||
| B | 54 (33.33) | 12 (28.57) | 0.557 |
| C | 108 (66.67) | 30 (71.43) |
- Citation: Ge GH, Ye Y, Zhou XB, Chen L, He C, Wen DF, Tan YW. Hepatitis B surface antigen levels of cessation of nucleos(t)ide analogs associated with virological relapse in hepatitis B surface antigen-negative chronic hepatitis B patients. World J Gastroenterol 2015; 21(28): 8653-8659
- URL: https://www.wjgnet.com/1007-9327/full/v21/i28/8653.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i28.8653