Clinical characteristics of Helicobacter pylori-negative drug-negative peptic ulcer bleeding

Table 3 Univariate and multivariate analysis between idiopathic and drug-induced peptic ulcer bleeding

	Idiopathic PUB (n = 20)	Drug-induced PUB (n = 74)	P value1	OR (95%CI)1	P value2	OR (95%CI)2
Age			< 0.01	0.16 (0.05-0.47)	< 0.01	0.12 (0.03-0.55)
≥ 60 yr	6	54
< 60 yr	14	20
Sex			< 0.01	19.00 (2.42-149.36)	0.06	8.59 (0.94-83.82)
Male	19	37
Female	1	37
Ulcer type			0.02	4.86 (1.37-17.29)	0.08	3.86 (0.85-17.55)
Duodenal ulcer	6	6
Others	14	68
Ulcer size			0.60	1.31 (0.48-3.58)	0.16	2.65 (0.68-10.29)
≥ 1.0 cm	12	39
< 1.0 cm	8	35
Re-bleeding case upon admission
Yes	6	2	< 0.01	15.43 (2.82-84.43)	< 0.01	19.76 (2.39-162.91)
No	14	72

¹P value and OR (95%CI) by univariate logistic regression analysis;

²P value and OR (95%CI) by multivariate logistic regression analysis. PUB: Peptic ulcer bleeding.