Retrospective Cohort Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jul 21, 2015; 21(27): 8373-8381
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8373
Table 1 Baseline characteristics of the study cohort
VariablesTotalNon-ACLFACLFP value
(n = 382)(n = 330)(n = 52)
Demographics
Sex
Female60 (15.7)49 (14.8)11 (21.2)0.2452
Male322 (84.3)281 (85.2)41 (78.8)
Age (yr)
< 40226 (59.2)207 (62.7)19 (36.5)< 0.0012
≥ 40156 (40.8)123 (37.3)33 (63.5)
Underlying disease
HBV carriers98 (25.7)93 (28.2)5 (9.6)0.0012
CHB255 (58.9)217 (65.8)38 (73.1)
Compensatory cirrhosis29 (7.6)20 (6.0)9 (17.3)
Biochemical indicators
ALT (U/L)746.9 (338.1, 1229.0)754.2 (361.6, 1215.7)644.4 (324.9, 1430.6)0.9243
AST (U/L)448.0 (217.7, 836.1)432.5 (216.1, 806.9)529.4 (273.8, 960.9)0.0913
TBil (μmol/L)
< 171234 (61.3)210 (63.6)24 (46.2)0.0162
≥ 171148 (38.7)120 (36.4)28 (53.8)
PTA (%)
> 60184 (48.1)181 (54.8)3 (5.8)< 0.0012
50.1-60124 (32.5)100 (30.3)24 (46.1)
40-5074 (19.4)49 (14.9)25 (48.1)
ALB4 (g/L)37.2 ± 4.837.4 ± 4.636.0 ± 5.30.0431
CHE (U/L)4801.8 ± 1645.54864.2 ± 1559.14666.2 ± 1840.40.4201
K (mmol/L)3.91 ± 0.443.92 ± 0.443.90 ± 0.410.8261
Na (mmol/L)138.7 ± 2.9138.8 ± 2.9137.6 ± 2.80.0041
Cr5 (μmol/L)67.6 ± 14.567.6 ± 12.767.1 ± 22.70.8131
Virology indicators
HBeAg6 (IU/mL)
Negative88 (23.0)73 (22.1)15 (28.8)0.3682
Positive280 (73.3)243 (73.6)37 (71.2)
HBV DNA (copies/mL)
< 106153 (40.1)144 (43.6)9 (17.3)< 0.0012
106-107104 (27.2)93 (28.2)11 (21.2)
> 107125 (32.7)93 (28.2)32 (61.5)