TLR4-HMGB1-, MyD88- and TRIF-dependent signaling in mouse intestinal ischemia/reperfusion injury

doi:10.3748/wjg.v21.i27.8314

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 21, 2015; 21(27): 8314-8325
Published online Jul 21, 2015. doi: 10.3748/wjg.v21.i27.8314

Table 3 Levels of myeloperoxidase activity in the lung and liver (mean ± SD)

Group (n = 4)	Lung	Liver
Sham	0.30 ± 0.12	0.25 ± 0.03
Control	0.76 ± 0.06^a	0.68 ± 0.08^a
Anti-HMGB1	0.46 ± 0.06^a^b	0.40 ± 0.07^a^b
Anti-MyD88	0.63 ± 0.03^a^b^c	0.55 ± 0.03^a^b^c
Anti-TRIF	0.57 ± 0.06^a^b^c	0.50 ± 0.04^a^b^c

^aP < 0.05 vs sham group;

^bP < 0.05 vs control group;

^cP < 0.05 vs anti-HMGB1 group. HMGBI: High-mobility group protein 1; MyD88: Myeloid differentiation gene 88; TRIF: Translocating-chain-associating membrane protein.

Citation: Wang J, He GZ, Wang YK, Zhu QK, Chen W, Guo T. TLR4-HMGB1-, MyD88- and TRIF-dependent signaling in mouse intestinal ischemia/reperfusion injury. World J Gastroenterol 2015; 21(27): 8314-8325
URL: https://www.wjgnet.com/1007-9327/full/v21/i27/8314.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i27.8314