Conjugation of toll-like receptor-7 agonist to gastric cancer antigen MG7-Ag exerts antitumor effects

Figure 6 Vaccines induced cytotoxic T cell responses. Lymphocytes were separated from the spleens of mice immunized with vaccines or PBS as control. Cytotoxic T lymphocyte activities were indicated by lysis of Ehrlich ascites carcinoma (EAC) cells using the lactate dehydrogenase method. Data are presented as mean ± SE (n = 5); ^bP < 0.01 vs control group; ^cP < 0.05 vs T7+MG3 group. MG1: Monoclonal gastric cancer 7 antigen mono-epitope; MG3: Monoclonal gastric cancer 7 antigen tri-epitope; T7: Toll-like receptor-7 agonist.