Changes in gene expression in liver tissue from patients with fulminant hepatitis E

doi:10.3748/wjg.v21.i26.8032

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 14, 2015; 21(26): 8032-8042
Published online Jul 14, 2015. doi: 10.3748/wjg.v21.i26.8032

Table 1 Characteristics of study subjects in the three groups

Characteristic	Healthy controls (n = 6)	Fulminant hepatitis B (n = 6)	Fulminant hepatitis E (n = 5)
Age (yr)	52 (30-58)	24 (16-60)	28 (18-32)
Gender (Male:Female)	4:2	4:2	1:4
Duration of illness before death (d)	-	9 (6-14)	10 (7-13)
Maximum total serum bilirubin (mg/dL)	0.7 (0.4-1.4)	21 (13.1-41.4)	25 (5.4-32.0)
Serum ALT^a (IU/L)	30 (21-58)	1939 (524-5795)	770 (240-1302)
Serum AST (IU/L)	28 (18-35)	859 (250-2345)	458 (332-1000)
Alkaline phosphatase (IU/L)	-	257 (131-427)	306 (164-561)
Serum albumin (g/dL)	-	2.8 (2.0-3.3)	2.8 (2.1-3.2)

Data are shown as median (range), except for gender distribution; patients with fulminant hepatitis B and fulminant hepatitis E were comparable in all variables except serum ALT levels (^aP < 0.05, Mann-Whitney U test). ALT: Alanine aminotransferase.

Citation: Naik A, Goel A, Agrawal V, Sarangi AN, Chhavi N, Singh V, Jameel S, Aggarwal R. Changes in gene expression in liver tissue from patients with fulminant hepatitis E. World J Gastroenterol 2015; 21(26): 8032-8042
URL: https://www.wjgnet.com/1007-9327/full/v21/i26/8032.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i26.8032