Resolution of non-alcoholic steatohepatitis by rosuvastatin monotherapy in patients with metabolic syndrome

Figure 1 Presentation of the baseline and repeat liver biopsies in 3 metabolic syndrome patients with non-alcoholic steatohepatitis on rosuvastatin (10 mg/d) monotherapy for 12 mo. On the left panel liver biopsies of patients with non-alcoholic steatohepatitis presenting steatosis (fat content of the liver > 30%), hepatocyte ballooning degeneration, diffuse lobular mixed acute and chronic inflammation, and perivenular, perisinusoidal collagen disposition. On the right panel liver biopsies of the same 3 patients after one year monotherapy with 10 mg/d of rosuvastatin presenting total normal liver tissue.