Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats

doi:10.3748/wjg.v21.i25.7777

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2015; 21(25): 7777-7785
Published online Jul 7, 2015. doi: 10.3748/wjg.v21.i25.7777

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Figure 6 Immunohistochemical staining for TORC2 in the liver tissues. Optical microscopy image of TORC2 is shown in brown. The normal group (A) exhibited little TORC2 in the nuclei. However, more TORC2 was present in the nuclei of the model group (B). The groups treated with Berberine (C), AICAR (D) and Metformin (E) exhibited lower levels of TORC2 compared to the model group (magnification × 400).

Citation: Jiang SJ, Dong H, Li JB, Xu LJ, Zou X, Wang KF, Lu FE, Yi P. Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats. World J Gastroenterol 2015; 21(25): 7777-7785
URL: https://www.wjgnet.com/1007-9327/full/v21/i25/7777.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i25.7777