Ezetimibe improves hepatic steatosis in relation to autophagy in obese and diabetic rats

Figure 2 Ezetimibe increases autophagy makers in OLETF liver tissue. mRNA level (A) and protein expression (B and C) was measured and expressed as the fold change compared to OLETF control. ATG 5 and 6 protein expression was normalized by α-tubulin and LC3 protein abundance was expressed as the ratio between LC3-II (14 kDa) and LC3-I (16 kDa). Results are presented as mean ± SE. ^aP < 0.05, ^bP < 0.01 vs OLETF control. ATG: Autophagy-related gene; LETO con: LETO control; OLETF con: OLETF control; OLETF Ez: OLETF ezetimibe.