TLR2 and TLR4 polymorphisms influence mRNA and protein expression in colorectal cancer

Figure 4 Densitometry values of immunohistochemistry analysis for toll-like receptor 2 and toll-like receptor 4 proteins, stratified according to polymorphic and wild genotypes. Carriers of the polymorphic genotype del/del for TLR2-196 to -174del polymorphism showed higher protein expression than those with homozygous wild genotype ins/ins (^aP = 0.03). No statistical difference was found for the values ​​of TLR4 protein. ins: Wild-type allele (insertion); del: Polymorphic allele (deletion).