TLR2 and TLR4 polymorphisms influence mRNA and protein expression in colorectal cancer

Figure 1 Distribution of the median mRNA relative quantification values of genes TLR2 and TLR4. Using the Wilcoxon’s signed rank test, a statistically significant difference was found for TLR2 (^bP < 0.0001), but not for TLR4 (P = 0.452), when comparing the relative quantification (RQ) in colorectal cancer tissue (CRC) with adjacent normal tissue pools (NT). The reference genes ACTB and GAPDH were used as endogenous controls.