TLR2 and TLR4 polymorphisms influence mRNA and protein expression in colorectal cancer

Table 6 TLR2 and TLR4 mRNA relative quantification values in colorectal carcinoma, stratified according to wild and polymorphic genotype

	TLR2 -196 to -174 del		TLR4 -1607 T/C
	ins/ins	ins/del2	T/T	T/C + C/C
n (%)1	27 (73.0)	10 (27.0)	31 (83.8)	6 (16.2)
Median	3.57	6.95	0.75	0.86
Range	0.49-13.59	0.62-14.69	0.20-23.89	0.47-2.27
P value3	0.035		1.000

¹3 tumor tissue samples which were not genotyped were excluded from the analysis; ²No individuals with a del/del genotype in tumor tissue samples were found;

³Results of the nonparametric Mann-Whitney U test. ins: Wild-type allele (insertion); del: Polymorphic allele (deletion).