TLR2 and TLR4 polymorphisms influence mRNA and protein expression in colorectal cancer

Table 1 Characteristics of patients with colorectal cancer and controls n (%)

Variables	CRC	Controls	OR (95%CI)	P value
Individuals, n	194	240
Age (yr)			0.4513 (0.3063-0.6649)
< 60	72 (37.1)	136 (56.7)		< 0.0001
≥ 60	122 (62.9)	104 (43.3)
mean ± SD	62 ± 12	56 ± 18
Variation	24 to 88	20 to 93
Gender			0.8619 (0.5898-1.259)	0.4988
Female	89 (45.9)	119 (49.6)
Male	105 (54.1)	121 (50.4)
Smoking habit			1.910 (1.299-2.808)	0.0013
Non-smokers	101 (52.1)	87 (36.3)
Smokers	93 (47.9)	153 (63.7)
Alcoholic habit			0.4963 (0.3305-0.7454)	0.0010
Non-alcoholic	114 (58.8)	178 (74.1)
Alcoholics	80 (41.2)	62 (25.9)

CRC: Colorectal cancer; OR: Odds ratio.