Grape seed proanthocyanidin protects liver against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress

Figure 5 Effects of grape seed proanthocyanidin on the protein expression of endoplasmic reticulum stress proteins in the liver. The expression of glucose-regulated protein (GRP)78, inositol-requiring enzyme (IRE)-1, nuclear factor (NF)-κb, procaspase-12, activating transcription factor (ATF)-4, and CCAAT/enhancer-binding protein homologous protein (CHOP) was assessed by Western blotting after ischemia/reperfusion (IR) and with grape seed proanthocyanidin (GSP) treatment. GAPDH was used as a loading control.