Immunohistochemical CD3 staining detects additional patients with celiac disease

Table 1 Marsh classification of duodenal biopsies on hematoxylin and eosin stains versus CD3 stains n (%)

Evaluation of the stains	Evaluation of CD3 stains
	Positive1			Negative
	Marsh III	Marsh II	Marsh I	No CD
	(n = 93)	(n = 3)	(n = 13)	(n = 50)
Marsh III (n = 87)	86 (98.9)	-	-	1 (1.1)
Marsh II (n = 1)	-	1 (100)	-	-
Marsh I (n = 6)	1 (16.7)	-	4 (66.7)	1 (16.7)
No CD (n = 65)	6 (9.2)	2 (3.1)	9 (13.8)	48 (73.8)

¹≥ 30 intraepithelial lymphocytes per 100 epithelial cells. HE: Hematoxylin and eosin; CD: Celiac disease.