Integrin αvβ6 sustains and promotes tumor invasive growth in colon cancer progression

Table 3 Five year survival estimates for 100 patients with colon cancer

Groups	Negative/positive	n	Median survival (mo) and 95%CI	5-yr survival rate (%) and 95%CI
αvβ6	Negative	62	45.948 (40.575-51.320)	0.585 (0.452-0.718)
	Positive	38	36.114 (28.501-43.728)	0.402 (0.220-0.584)1
MMP-9	Negative	32	44.071 (36.812-51.330)	0.570 (0.392-0.748)
	Positive	68	41.686 (36.040-47.331)	0.485 (0.344-0.626)2

¹Log-rank test indicates a significant survival difference between negative vs positive integrin ανβ6 expression groups (χ² = 3.919; P = 0.048; P < 0.05);

²There was no significant difference between negative vs positive MMP-9 expression groups (χ² = 0.451; P = 0.502; P > 0.05). ανβ6: Integrin ανβ6; MMP-9: Matrix metalloproteinase-9.