Liver fibrosis markers of nonalcoholic steatohepatitis

Table 2 Liver fibrosis markers developed for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

Liver fibrosis markers for NAFLD	Items	Cohort	AUROC for diagnosis	Ref.
HAIR	Hypertension, ALT, insulin resistance	105	Stage 3-4: 0.90	Dixon et al[47], 2001
BAAT score	BMI, Age, ALT, Triglycerides	93	Stage 2-4: 0.84	Ratziu et al[48], 2000
NAFLD Fibrosis score	Age, BMI, Hyperglycemia, Platelet count, Albumin, AST/ALT ratio	733	Stage 3-4: 0.84	Angulo et al[49], 2007
BAAD score	BMI, AST/ALT ratio, DM	827	Stage 3-4: 0.81	Harrison et al[51], 2008
FibroMeter NAFLD	Glucose, AST, Platelet count, ALT, Ferritin, Body Weight, Age	235	Stage 2-4: 0.943	Calès et al[52], 2009
NAFLD Diagnostic Panel	DM, Gender, BMI, Triglycerides, CK18 fragments (apoptotic and necrotic)	79	1Stage 1-4: 0.81,2Stage 2-4: 0.80	Younossi et al[54], 2011
NAFIC score	Ferritin, IRI, type IV collagen 7S	619	Stage 2-4: 0.834, Stage 3-4: 0.869	Sumida et al[53], 2011

¹Presence of any degree of fibrosis;

²Presence of advanced fibrosis (at least moderate portal or pericellular fibrosis, bridging fibrosis, or cirrhosis). NAFLD: Nonalcoholic fatty liver disease.