Recombinant streptokinase vs hydrocortisone suppositories in acute hemorrhoids: A randomized controlled trial

doi:10.3748/wjg.v21.i23.7305

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

World J Gastroenterol. Jun 21, 2015; 21(23): 7305-7312
Published online Jun 21, 2015. doi: 10.3748/wjg.v21.i23.7305

Table 3 Subgroup analyses: 5^th day complete response

	I: rSK schedule A	II: rSK schedule B	III: Hydrocortisone	P value¹
Type of acute event
Without thrombosis	42/48 (87.5)	36/41 (87.8)	10/37 (27.0)	< 0.0001
With thrombosis	114/122 (93.4)	119/129 (92.2)	36/133 (27.1)	< 0.0001
Thrombectomy	2/122 (1.6)	2/129 (1.6)	14/133 (10.5)	< 0.001
Hemorrhoid classification
External	96/103 (93.2)	100/112 (89.3)	19/112 (17.0)	< 0.0001
Internal + mixed	60/67 (89.6)	55/58 (94.8)	27/58 (46.6)	< 0.0001
Prolapse grade
I or II	49/54 (91)	35/37 (95)	21/43 (49)	< 0.0001
III or IV	11/13 (85)	20/21 (95)	6/15 (40)	< 0.001

¹Likelihood ratio χ². rSK: Recombinant streptokinase.

Citation: Hernández-Bernal F, Castellanos-Sierra G, Valenzuela-Silva CM, Catasús-Álvarez KM, Martínez-Serrano O, Lazo-Diago OC, Bermúdez-Badell CH, Causa-García JR, Domínguez-Suárez JE, Investigators PALST4(OHWRSAGO. Recombinant streptokinase vs hydrocortisone suppositories in acute hemorrhoids: A randomized controlled trial. World J Gastroenterol 2015; 21(23): 7305-7312
URL: https://www.wjgnet.com/1007-9327/full/v21/i23/7305.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i23.7305