Recombinant streptokinase vs hydrocortisone suppositories in acute hemorrhoids: A randomized controlled trial

Table 2 Results of clinical evaluations after treatment

	I: rSK schedule A	II: rSK schedule B	III: Hydrocortisone	P value
n	170	170	170
Response after 3 d	117 (68.8)	109 (64.1)	12 (7.1)	< 0.0011
Response after 5 d (95%CI)	156 (91.8) (87.3-96.2)	155 (91.2) (86.6-95.7)	46 (27.1) (20.1-34.0)	< 0.0011
Difference with III (95%CI)	64.6 (56.7-72.2)	63.9 (55.7-72.0)
Response after 10 d	165 (97.1)	159 (93.5)	114 (67.1)	< 0.0011
Days to response, median (95%CI)	3 (2.9-3.1)	3 (2.9-3.1)	10 (9.3-10.7)	< 0.0012

¹Likelihood ratio χ²;

² Log-rank test. Main outcome are represented in bold. rSK: Recombinant streptokinase.