High level of intercellular adhesion molecule-1 affects prognosis of patients with hepatocellular carcinoma

Table 4 Cox multivariate proportional hazard model of independent predictors on disease-free and overall survival

Variable	Disease-free survival		Overall survival
	HR (95%CI)	P value	HR (95%CI)	P value
ICAM-1 (ng/mL) (> 684 vs ≤ 684)	1.643 (1.125-2.401)	0.010	1.692 (1.152-2.486)	0.007
Tumor number (multiple vs single)	1.324 (0.902-1.944)	0.152	1.273 (0.924-1.755)	0.140
TNM stage (III-IV vs  I-II)	1.390 (0.931-2.077)	0.108	1.468 (1.074-2.015)	0.016
PVTT (yes vs no)	1.397 (1.016-1.920)	0.040	1.514 (1.031-2.225)	0.035
Tumor size (cm) (> 5 vs ≤ 5)	0.666 (0.389-1.149)	0.144	1.551 (0.899-2.656)	0.115
NLR (> 2.31 vs ≤ 2.31)	1.578 (1.156-2.153)	0.004	1.485 (1.086-2.030)	0.013

ICAM-1: Intercellular adhesion molecule-1; TNM: Tumor-node-metastasis; PVTT: Portal vein tumor thrombus; NLR: Neutrophil-to-lymphocyte ratio.