Induction of endoplasmic reticulum-derived oxidative stress by an occult infection related S surface antigen variant

Figure 5 Down-regulation of anti-oxidant proteins by an occult infection related to an S surface antigen variant (KD). After transient transfection of plasmids (MOCK, NOR, and KD) into HuH-7 cells, the down-regulation of four anti-oxidant proteins, MnSOD, CuZnSOD, HO-1, and catalase in the KD variant was confirmed using Western blot. The results of the KD variant contrasted MOCK and NOR. The relative intensity values were determined, and all data are expressed as the mean ± SD within a group. The three experiments were compared using Tukey’s multiple post-hoc test (^aP < 0.05, ^bP < 0.01 vs three experiments).