Clinical impact of preoperative acute pancreatitis in patients who undergo pancreaticoduodenectomy for periampullary tumors

Table 5 Risk factors influencing severe complications after pancreaticoduodenectomy by univariate and multivariate logistic regression analyses

Parameter	Univariate1		Multivariate1
	OR (95%CI)	P value	OR (95%CI)	P value
Age (≥ 70 yr vs < 70 yr)	0.68 (0.15-3.17)	0.623
Sex (male vs female)	2.46 (0.67-9.06)	0.175
Weight loss (yes vs no)	1.14 (0.40-3.28)	0.810
Preoperative jaundice (yes vs no)	0.85 (0.29-2.49)	0.762
Preoperative acute pancreatitis (yes vs no)	3.87 (1.30-11.46)	0.015	4.70 (1.48-14.96)	0.009
Preoperative biliary drainage (yes vs no)	2.55 (0.65-10.1)	0.181
Comorbid disease (yes vs no)	2.78 (0.95-8.07)	0.061	3.72 (1.18-11.75)	0.025
Intraoperative blood transfusion (yes vs no)	2.92 (0.99-8.61)	0.052	3.50 (1.11-10.97)	0.032
Histology (pancreatic vs other)	0.74 (0.26-2.13)	0.578

¹Logistic regression. NS: Not significant.