Prognostication and response assessment in liver and pancreatic tumors: The new imaging

Table 2 Data derived from the main published studies that have correlated apparent diffusion coefficient quantification with the pathological grade of pancreatic ductal adenocarcinomas and neuroendocrine tumors

Study	n	b values(s/mm2)	Histotype	mean ADC value(× 10-3 mm2/s)
Wang et al[43]	21	0, 500	PDAC	2.10 (WD-MD); 1.46 (PD)
Legrand et al[44]	22	Multiple1	PDAC	1.43 (WD); 1.94 (MD-PD)
Rosenkrantz et al[45]	30	0, 500	PDAC	1.78/1.75 (WD-MD); 1.69/1.62 (PD)2
Wang et al[58]	18	0, 50, 500	PanNET	1.75 (G1); 1.00 (G3)
Jang et al[59]	20	0, 800	PanNET	1.48 (G1-G2); 1.04 (G3)
Hwang et al[60]	44	Multiple3	PanNET	1.31 (G1); 1.08 (G2-G3)

¹50, 200, 400, 600, 800 s/mm²;

²Two readers;

³0, 25, 50, 75, 100, 150, 200, 500, 800, 1000 s/mm². n: Number of patients; ADC: Apparent diffusion coefficient; PDAC: Pancreatic ductal adenocarcinoma; WD: Well differentiated; PanNET: Pancreatic neuroendocrine tumor; MD: Moderately differentiated; PD: Poorly differentiated.