Prognostication and response assessment in liver and pancreatic tumors: The new imaging

Table 1 Data derived from the main published studies that have tested correlations between apparent diffusion coefficient values and pathological grade of hepatocellular carcinomas

Study	Number of patients	b values(s/mm2)	mean ADC value(× 10-3 mm2/s)
Nasu et al[23]	99	0, 500	1.45 (WD); 1.46 (MD); 1.36 (PD)
Piana et al[24]	99	0, 500	1.29 (WD); 1.22 (MD); 1.21 (PD)
Saito et al[25]	32	100, 800	1.25 (WD); 1.12 (MD); 1.13 (PD)
Muhi et al[26]	73	500, 800	0.91 (WD); 0.71 (MD); 0.68 (PD)
Nishie et al[27]	80	0, 500, 1000	1.21 (WD); 1.14 (MD); 0.76 (PD)
Heo et al[28]	27	0, 1000	1.20 (WD); 1.10 (MD); 0.90 (PD)
Nakanishi et al[29]	44	0, 50, 1000	1.29 (MD); 1.07 (PD)

ADC: Apparent diffusion coefficient; WD: Well differentiated; MD: Moderately differentiated; PD: Poorly differentiated.