Low G preconditioning reduces liver injury induced by high +Gz exposure in rats

Figure 2 Pathological changes in the liver tissue at 0 and 6 h after +Gz exposures in the blank control group, low G preconditioning group and +10 Gz/5 min group. No significant injury was found in blank control group (A: Suzuki’s score = 2.12 ± 0.13). At 0 h after exposure, there was disorderly hepatic sinus cord-like structure associated with hepatocyte edema in +10 Gz/5min (10G) group (B: Suzuki’s score = 3.23 ± 0.37). In sharp contrast, there was regular liver lobule structure in low G preconditioning (LG) group (C: Suzuki’s score = 2.28 ± 0.16). At 6 h after exposure, hepatocyte edema became lighter, and liver lobule structure had orderly arrangement in 10G group (E: Suzuki’s score = 2.53 ± 0.25; P < 0.01). There was no significant difference between 0 and 6 h after exposure in LG group (C and D: Suzuki’s score = 2.28 ± 0.16 vs 2.31 ± 0.14, P < 0.01). BC: Blank control.