Proportions of acetyl-histone-positive hepatocytes indicate the functional status and prognosis of cirrhotic patients

Table 3 Univariate and multivariate analyses of risk factors for patient survival

Variable	Unitivariate analysis			Multivariate analysis
	OS (%)	95%CI	P value	HR	95%CI	P value
Age (yr)
< 60	75.0	66.2-83.8	0.035	0.35	0.12-1.04	0.059
> 60	49.4	24.1-74.7
Gender					0.858-6.009
Female	75.1	59.0-91.2	0.171	2.27		0.099
Male	69.0	59.2-78.8
CTP grade					0.26-8.56
A, B	72.0	153.8-179.7	0.041	1.36		0.744
C	50.0	10.0-89.9
Ascites					0.31-2.60	0.843
No	71.8	62.2-81.4	0.535	0.90
Yes	68.5	50.9-86.1
H2AK5ac					1.68-24.49
< 70%	94.7	88.6-100.8	0.000	6.41		0.007
> 70%	50.3	34.6-66.0
H3K9/K14ac				1.88	0.67-5.42
< 70%	83.4	72.2-94.6	0.000			0.240
> 70%	56.9	44.6-69.2
H3K27ac
< 70%	86.4	79.1-93.7	0.000	4.75	1.82-12.36	0.001
> 70%	40.4	22.9-57.8

OS: Overall survival; HR: Hazard ratio.