High morbidity in myocardial infarction and heart failure patients after gastric cancer surgery

Table 3 Univariate morbidity analysis of operative risk factors in patients with underlying heart disease n (%)

Factors	Patient	Complication	P value	OR
Age (yr)			0.11
> 70	103	19 (18.4)
≤ 70	118	33 (28)
Sex			0.85
Male	171	41 (24)
Female	50	11 (22)
OP risk by Cardiologist			0.34
low	31	5 (16.1)
moderate	103	27 (26.2)
high	21	7 (33.3)
ASA score			0.19
1	14	1 (7.1)
2	122	27 (22.1)
3	85	24 (28.2)
Preop anticoagulation Tx			1.00
No	104	24 (23.1)
Yes	117	28 (23.9)
Tumor location			0.12
Lower body	30	12 (40.0)
Middle body	65	15 (23.1)
Upper body	123	25 (20.5)
Whole stomach	2	0 (0)
Tumor size			0.62
> 4 cm	129	28 (21.7)
≤ 4 cm	87	22 (25.3)
Tumor depth1			0.11
T1 (mucosa, submucosa)	121	23 (29)
T2 (muscle)	21	5 (23.8)
T3 (subserosa)	36	8 (22.2)
T4 (serosa exposure, serosa invasion)	43	16 (37.2)
LN metastasis1			0.01
N0	141	25 (17.7)		1.0
N1 (1-2)	28	8 (28.6)		1.8
N2 (3-6)	24	6 (25)		1.5
N3 (7-)	28	13 (46.4)		4.0
TNM stage1			0.058
I	130	23 (17.7)
II	37	10 (28.927)
III	53	19 (35.8)
IV	1	0 (0)
Approach methods			0.12
Open gastrectomy	177	45 (25.4)
Laparoscopy assisted gastrectomy	44	7 (15.9)
Operation type			0.03
Subtotal gastrectomy	177	36 (20.3)		1.0
Total gastrectomy	44	16 (36.4)		1.3
Operation time			0.75
< 200	89	21 (23.6)
> 200	109	29 (26.6)
LN dissection2			0.28
D1	12	3 (25)
D1+	47	7 (14.9)
D2	162	42 (25.9)
Combined organ resection			0.53
No	180	41 (22.8)
Yes	39	11 (28.2)
Preop chemotherapy			1.00
No	220	52 (23.6)
Yes	1	0 (0)

¹AJCC TNM stage 7^th edition;

²Japanese gastric cancer treatment guidelines 2010 (ver.3). LN: Lymph node; OP risk by cardiologist: Operation risk evaluated by cardiologist; ASA: American society of anesthesiologists; Preop: Preoperative; Tx: Treatment.