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©The Author(s) 2015.
World J Gastroenterol. Jun 7, 2015; 21(21): 6621-6630
Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6621
Published online Jun 7, 2015. doi: 10.3748/wjg.v21.i21.6621
Table 1 Correlation between RASSF6 expression and clinicopathological characters in patients with pancreatic ductal adenocarcinoma
Parameter | Total | RASSF6 | RASSF6 | RASSF6 | P value |
n = 96 | negative | weak | positive | ||
n = 51 | n = 29 | n = 16 | |||
Age (yr) | 0.115 | ||||
mean (range) | 60.7 (31-77) | 59.3 (77-45) | 61.3 (31-77) | 64.3 (54-70) | |
Gender | 0.563 | ||||
Male | 51 | 29 | 13 | 9 | |
Female | 45 | 22 | 16 | 7 | |
Location of tumor | 0.777 | ||||
Head | 81 | 42 | 22 | 13 | |
Body/tail | 15 | 9 | 7 | 3 | |
Differentiation | 0.138 | ||||
Well | 35 | 14 | 11 | 10 | |
Moderate | 37 | 22 | 12 | 3 | |
Poor | 24 | 15 | 6 | 3 | |
Tumor diameter (cm) | 0.613 | ||||
mean (range) | 3.7 (1.5-8.0) | 3.8 (1.5-8.0) | 3.5 (1.5-6.0) | 3.9 (7.5-5.5) | |
UICC/TNM stage | 0.200 | ||||
pI | 6 | 4 | 0 | 2 | |
pII | 90 | 47 | 29 | 14 | |
T-stage | 0.0471, 0.0762 | ||||
pT1 | 5 | 3 | 2 | 0 | |
pT2 | 10 | 3 | 2 | 5 | |
pT3 | 81 | 45 | 25 | 11 | |
N-stage | 0.124 | ||||
pN0 | 35 | 23 | 9 | 3 | |
pN1 | 61 | 28 | 20 | 13 | |
Portal vein invasion | 0.698 | ||||
Negative | 84 | 45 | 26 | 13 | |
Positive | 12 | 6 | 3 | 3 | |
Perineural invasion | 0.026 | ||||
Negative | 31 | 11 | 11 | 9 | |
Positive | 65 | 40 | 18 | 7 | |
Surgical margins | 0.694 | ||||
Negative | 79 | 43 | 24 | 12 | |
Positive | 17 | 8 | 5 | 4 |
- Citation: Ye HL, Li DD, Lin Q, Zhou Y, Zhou QB, Zeng B, Fu ZQ, Gao WC, Liu YM, Chen RW, Li ZH, Chen RF. Low RASSF6 expression in pancreatic ductal adenocarcinoma is associated with poor survival. World J Gastroenterol 2015; 21(21): 6621-6630
- URL: https://www.wjgnet.com/1007-9327/full/v21/i21/6621.htm
- DOI: https://dx.doi.org/10.3748/wjg.v21.i21.6621