Reversible sinusoidal obstruction syndrome associated with tacrolimus following liver transplantation

Table 1 Clinical characteristics during disease course

Days after LT	50	80	87	104	111	118
Clinical course		Current admission	Before defibrotide	After defibrotide/TAC withdrawal		Resolution
ALT (U/L)	17	35	39	43	26	23
TB (μmol/L)	16	20	57	76	42	13
Platelet (109/mL)	156	171	183	175	158	173
PT (s)	11.5	11.3	12.5	12.7	11.5	12.2
D-dimer (mg/L)	0.27	0.34	0.52	0.41	0.32	0.33
TAC (ng/mL)	7.9	8.9	7.2	5.6
CSA (ng/mL)					126	165
Wt (kg)	64.5	66.0	67.9	69.5	67.5	64.8

LT: Liver transplantation; ALT: Alanine aminotransferase; TB: Total bilirubin; PT: Prothrombin time; TAC: Tacrolimus; CSA: Cyclosporine A; Wt: Body weight.