Meta-Analysis
Copyright ©The Author(s) 2015.
World J Gastroenterol. May 28, 2015; 21(20): 6352-6360
Published online May 28, 2015. doi: 10.3748/wjg.v21.i20.6352
Table 3 Summary of most common adverse events (occurring in 10% or more of patients in any group)
Ref.GroupGeneral adverse events1
Ulcerative colitis aggravatedNausea/vomitingHeadacheFrequent bowel movementsFatigueUpper respiratory tract infectionAbdominal pain/tendernessArthralgiaDizzinessRash
Feagan et al[14]Intervention 129 (50)21 (36)12 (21)10 (17)8 (14)8 (14)10 (17)4 (7)6 (10)6 (10)
Intervention 222 (37)13 (22)11 (18)5 (8)5 (8)8 (13)6 (10)7 (12)4 (7)4 (7)
Control24 (38)15 (24)13 (21)10 (16)7 (11)5 (8)16 (25)5 (8)1 (2)4 (6)
Feagan et al[15]Intervention97 (13)38 (5)80 (11)NA33 (4)132 (18)50 (7)56 (8)NANA
Control58 (39)19 (13)28 (19)NA10 (7)47 (32)10 (7)25 (17)NANA
Parikh et al[16]Intervention 12 (17)NA2 (17)NANA4 (33)NANA1 (8)NA
Intervention 21 (7)NA3 (21)NANA3 (21)NANA0 (0)NA
Intervention 30 (0)NA2 (18)NANA1 (9)NANA0 (0)NA
Control4 (44)NA1 (11)NANA4 (44)NANA1 (11)NA
Feagan et al[14]Intervention 16 (10)NANANANANANA6 (10)18 (15)2
Intervention 23 (5)NANANANANANA12 (20)
Control8 (13)NANANANANANA6 (10)
Feagan et al[15]InterventionNA35 (5)13 (2)NANANANA77 (10)
ControlNA16 (11)36 (24)NANANANA37 (25)
Parikh et al[16]Intervention 1NANA0 (0)0 (0)0 (0)1 (8)0 (0)1 (8)2 (5)2
Intervention 2NANA2 (14)2 (14)2 (14)0 (0)0 (0)0 (0)
Intervention 3NANA0 (0)0 (0)0 (0)0 (0)1 (9)1 (9)
ControlNANA0 (0)0 (0)0 (0)1 (11)1 (11)0 (0)