E2F-1 overexpression inhibits human gastric cancer MGC-803 cell growth in vivo

Figure 2 Overexpression of E2F-1 inhibits MGC-803 tumor growth. A: Tumor growth curve shows the growth tendency in the LV-GFP-E2F-1 group is suppressed in comparison to the control groups; B: Relative tumor volume (TV) in LV-GFP-E2F-1-treated mice was significantly smaller than in the control groups at 12 d after tumor injection (n = 8 animals for each condition). 1, phosphate-buffered saline (PBS) control group; 2, LV-GFP-NC group; 3, LV-GFP-E2F-1 group; comparisons made using analysis of variance and Student-Newman-Keuls analyses; ^aP < 0.05 vs control.