Prophylaxis against hepatitis B virus recurrence after liver transplantation: A registry study

doi:10.3748/wjg.v21.i2.584

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2015; 21(2): 584-592
Published online Jan 14, 2015. doi: 10.3748/wjg.v21.i2.584

Table 5 Multivariate Cox proportional hazards analysis for posttransplant hepatitis B virus recurrence

Factor		Hazard ratio	95%CI	P value
Pre-LT with HCC	Yes vs No	1.718	1.243-2.375	0.001
Pre-LT serum HBV DNA ≥ 10⁵ copies/mL	Yes vs No	1.370	0.989-1.897	0.048
Pre-LT using ETV	Yes vs No	0.166	0.019-1.484	0.108
Post-LT HBV prophylactic protocol	HBIG + LAM vs HBIG + ETV	2.127	0.416-3.055	0.046
Donor profiles
Donor gender	Male vs Female	0.632	0.156-1.144	0.201
Donor HBsAb positivity	Positive vs Negative	0.526	0.265-1.045	0.066

LT: Liver transplantation; HCC: Hepatocellular carcinoma; HBV DNA: Hepatitis B virus deoxyribonucleic acid; ETV: Entecavir; HBIG: Hepatitis B immunoglobulin; LAM: Lamivudine; HBsAb: Hepatitis B surface antibody.

Citation: Shen S, Jiang L, Xiao GQ, Yan LN, Yang JY, Wen TF, Li B, Wang WT, Xu MQ, Wei YG. Prophylaxis against hepatitis B virus recurrence after liver transplantation: A registry study. World J Gastroenterol 2015; 21(2): 584-592
URL: https://www.wjgnet.com/1007-9327/full/v21/i2/584.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i2.584