Retrospective Study
Copyright ©The Author(s) 2015.
World J Gastroenterol. Jan 14, 2015; 21(2): 571-577
Published online Jan 14, 2015. doi: 10.3748/wjg.v21.i2.571
Table 3 Univariate analysis of potential risk factors for lymph node metastasis n (%)
Factor for lymph node metastasisPresence (n = 104)Absence (n = 1000)P value
Age (yr)0.049
< 6061 (58.7)485 (48.5)
≥ 6043 (41.3)515 (51.5)
Gender0.003
Male53 (51.0)656 (65.6)
Female51 (49.0)344 (34.4)
Size of tumor (mm)< 0.0001
< 20 mm9 (8.7)370 (37.0)
≥ 20 mm95 (91.3)630 (63.0)
Location0.389
Upper third9 (8.7)116 (11.6)
Middle third36 (34.6)289 (28.9)
Lower third59 (56.7)595 (59.5)
Macroscopic type< 0.0001
Elevated7 (6.7)78 (7.8)
Flat1 (1.0)80 (8)
Depressed72 (69.2)743 (74.3)
Mixed24 (23.1)98 (9.8)
Depth of invasion< 0.0001
Mucosa24 (23.1)601 (60.1)
Submucosa80 (77.0)399 (39.9)
Sm111 (10.6)139 (13.9)
Sm234 (32.7)123 (12.3)
Sm335 (33.7)137 (13.7)
Ulceration0.222
Absent86 (9.0)872 (91.0)
Present18 (12.1)128 (85.9)
Lymphovascular invasion< 0.0001
Absent44 (42.3)911 (91.1)
Present60 (57.7)89 (8.9)
Histological type< 0.0001
Well differentiated4 (3.8)232 (23.2)
Moderate differentiated45 (43.3)352 (35.2)
Poorly differentiated36 (34.6)208 (20.8)
Signet ring cell19 (18.3)208 (20.8)