Histological mixed-type as an independent prognostic factor in stage I gastric carcinoma

Table 2 Univariate and multivariate survival analyses using Cox’s proportional hazard model in pathological stage I gastric cancer

Variables	Univariate1	Multivariate2
	P value	HR	95%CI		P value
Sex
Male vs female	0.5618
Age (yr)
≥ 65 vs < 65	0.1001
Location
U vs ML	0.8450
Histological type (JCGC)
Undiff vs Diff	0.7256
Tumor size (mm)
≥ 25 vs < 25	0.1918
Venous invasion
Positive vs Negative	< 0.00013	13.513	2.252	83.33	0.00443
Lymphatic invasion
Positive vs Negative	0.1796
pT-stage
T2 vs T1	0.4781
pN-stage
N1 vs N0	0.6373
Histological type
Mixed vs Non-mixed	0.00263	11.402	1.265	102.74	0.03003

¹Kaplan-Meier method, and statistical significance was determined by log-rank test;

²multivariate survival analysis was performed using Cox’s proportional hazard model;

³Statistically significant values (P < 0.05). Diff: Differentiated; Undiff: Undifferentiated.