Hepatocyte nuclear factor 4α induces a tendency of differentiation and activation of rat hepatic stellate cells

Figure 4 Hepatocyte nuclear factor 4α mediated change of epithelial-mesenchymal transition phenotypic markers in hepatic stellate cells. After transfection of adenoviruses AdHNF4α and AdGFP, the expression of vimentin and E-cadherin was detected by RT-PCR, and relative expression was calculated by image density analysis normalized with the expression levels in HSC-T6 parental cells. HNF4α: Hepatocyte nuclear factor 4α; HSCs: Hepatic stellate cells.