Associations between CD24 gene polymorphisms and inflammatory bowel disease: A meta-analysis

Table 3 Meta-analysis of the associations between two promoter polymorphisms of CD24 and inflammatory bowel disease

Polymorphism	Disease	Test of association			Test of heterogeneity
		OR	95%CI	P value	Model	P value	I2(%)
P170V vs A	CD	1.16	0.69-1.93	0.583	R	0.100	63.0
	UC	1.49	0.81-2.77	0.203	R	0.012	84.3
	IBD	1.39	0.73-2.64	0.314	R	0.004	87.7
VV + AV vs AA	CD	0.76	0.28-2.07	0.594	R	0.019	81.9
(recessive)	UC	0.59	0.21-1.70	0.330	R	0.001	90.5
	IBD	0.64	0.21-1.90	0.420	R	< 0.001	92.8
VV vs AA + AV	CD	1.32	0.83-2.11	0.245	F	0.527	0.0
(dominant)	UC	1.79	1.15-2.77	0.009	F	0.816	0.0
	IBD	0.94	0.62-1.43	0.777	F	0.287	11.8
VV vs AA	CD	1.23	0.76-1.99	0.405	F	0.888	0.0
(additive)	UC	1.87	1.19-2.93	0.007	F	0.272	17.1
	IBD	1.32	0.40-4.39	0.654	R	0.051	73.9
P1527del vs TG	CD	1.24	1.01-1.52	0.037	F	0.101	56.5
	UC	0.95	0.76-1.19	0.649	F	0.967	0.0
	IBD	1.18	0.99-1.41	0.063	F	0.803	0.0
deldel + TGdel vs TGTG	CD	0.80	0.63-1.02	0.068	F	0.207	36.5
(recessive)	UC	1.02	0.79-1.33	0.870	F	0.980	0.0
	IBD	0.82	0.67-1.01	0.061	F	0.870	0.0
deldel vs TGTG + TGdel	CD	1.87	0.81-4.32	0.143	F	0.133	55.7
(dominant)	UC	0.40	0.10-1.63	0.201	F	0.345	0.0
	IBD	1.23	0.54-2.76	0.625	F	0.436	0.0
deldel vs TGTG	CD	1.93	0.84-4.47	0.123	F	0.121	58.4
(additive)	UC	0.40	0.10-1.64	0.203	F	0.348	0.0
	IBD	1.27	0.56-2.86	0.572	F	0.439	0.0

IBD: Inflammatory bowel disease; UC: Ulcerative colitis; CD: Crohn’s disease.