Prognostic value and clinical correlations of 18-fluorodeoxyglucose metabolism quantifiers in gastric cancer

Table 4 Analysis of accuracy of metabolic quantifiers to differentiate between local and disseminated tumours by ROC model

Metabolic quantifier	AUC	SE	95%CI	Cutoff value	Sensitivity of cutoff value	Specifity of cutoff value	Overall mark	P value
TLG30(cm3)1	0.781	0.071	0.63-0.921	390.531	65%1	78%1	Fair1	0.00061
SUVmean1	0.731	0.081	0.58-0.891	6.871	35%1	100%1	Fair1	0.09001
TLG2.5(cm3)1	0.721	0.081	0.55-0.881	802.171	53%1	83%1	Fair1	0.03401
MTV40(cm3)1	0.711	0.081	0.55-0.871	37.251	88%1	61%1	Fair1	0.00101
MTV30(cm3)	0.69	0.08	0.53-0.86	83.54	65%	74%	Poor	0.0020
MTV2.5(cm3)	0.68	0.09	0.51-0.84	132.55	59%	74%	Poor	0.0600
MTVliv(cm3)	0.67	0.09	0.50-0.84	87.12	53%	74%	Poor	0.1000
SUVmax	0.61	0.09	0.43-079	14.44	47%	78%	Poor	0.4000
TLGliv(cm3)	0.61	0.09	0.43-0.79	7.42	71%	56%	Poor	0.3000
TLG40(cm3)	0.50	0.09	0.31-0.68	49.26	6%	100%	Useless	-
COV	0.50	0.09	0.27-0.63	1.13	0%	96%	Useless	-

¹Parameters rated as “fair” or better. Overall mark by AUC value: 1.0 ideal, 0.99-0.9 excellent, 0.89-0.8 good, 0.79-0.7 fair, 0.69-0.51 poor, 0.5 useless (ideally random). SUV: Standard uptake volume; MTV: Metabolic tumour volume; COV: Coefficient of variation; TLG: Total lesion glycolysis; AUC: Area under curve.