Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA

doi:10.3748/wjg.v21.i19.5831

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 21, 2015; 21(19): 5831-5842
Published online May 21, 2015. doi: 10.3748/wjg.v21.i19.5831

Table 1 Normalized signal intensity and mean enhancement ratio of the pancreas in the diabetic rat group (n = 6) and the control rat (n = 5) group

	Pre	Imm after Gd-DOTA	3 min after Gd-DOTA	Imm after GdP	30 min after GdP	24 h after GdP
Normalized signal intensity of the pancreas
Control rats	137.9 (132.0, 152.4)	165.6 (160.0, 177.8)	158.2 (141.2, 161.3)	238.4 (201.8, 311.6)	264.7 (212.5, 280.7)^b	171.0 (147.3, 178.9)
Diabetic rats	146.6 (135.2, 161.7)	184.4 (164.0, 218.7)	173.3 (153.2, 185.9)	277.1 (217.0, 317.4)	302.6 (295.6, 353.3)^b	177.9 (145.9, 189.7)
Enhancement ratio of the pancreas (%)
Control rats		20.5 (8.7, 27.9)	9.3 (-7.3, 21.6)	80.8 (46.3, 111.2)	79.5 (54.1, 101.6)^a	17.4 (11.6, 24.0)
Diabetic rats		29.3 (11.8, 45.5)	14.8 (4.9, 34.4)	79.3 (47.5, 129.3)	103.3 (87.9, 151.1)^a	16.5 (-0.1, 34.8)

Data are shown as the median (lowest value, highest value). P values were calculated using the Mann-Whitney test. Imm: immediate; GdP: Gadofluorine P.

^aP < 0.05 control rats vs diabetic rats;

^bP < 0.01 control rats vs diabetic rats.

Citation: Cho HR, Lee Y, Doble P, Bishop D, Hare D, Kim YJ, Kim KG, Jung HS, Park KS, Choi SH, Moon WK. Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA. World J Gastroenterol 2015; 21(19): 5831-5842
URL: https://www.wjgnet.com/1007-9327/full/v21/i19/5831.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i19.5831