Phycocyanobilin accelerates liver regeneration and reduces mortality rate in carbon tetrachloride-induced liver injury mice

Figure 3 Phycocyanobilin reduces hepatocellular necrosis and apoptosis. A: Liver section of control group stained with HE at day 2 after CCl₄ injection of mice, showing partial necrosis with clusters of inflammatory cells around central vein; B: Liver section of PCB group stained with HE at day 2 after CCl₄ injection of mice, demonstrating decreased inflammatory cells and histological recovery compared with control group. In the TUNEL assay earthy yellow cells indicate apoptotic cells; C: The control group; D: PCB treated group; E: Demonstrated numbers of apoptotic cells. At least six 12 mm² tissue sections were counted for each group. Values represent mean ± SE (n = 6), ^bP < 0.01 vs control.