Association of IL-17 polymorphisms with gastric cancer risk in Asian populations

Table 1 Characteristics of the included studies focusing on IL-17 genetic polymorphisms

Ref.	Year	Country	Sample size		Gender (M/F)		Age (yr)		Genotyping methods	Gene	SNP	STROBE
			Case	Control	Case	Control	Case	Control
Wu et al[30]	2014	China	945	768	-	-	-	-	PCR-RFLP	IL-17A	rs2275913 G>A	29
Zhang et al[23]	2014	China	260	512	162/98	280/232	60.6 ± 10.7	51.3 ± 11.2	Sequenom MassArray	IL-17A	rs2275913 G>A	30
											rs763780 T>C
Zhu et al[2]	2014	China	293	550	189/104	312/238	57.5 ± 11.3	56.7 ± 12.7	Sequenom MassArray	IL-17A	rs2275913 G>A	31
										IL-17F	rs763780 T>C
Rafiei et al[7]	2013	Iran	161	171	89/72	84/87	62.6 ± 12.4	60.8 ± 12.8	PCR-RFLP	IL-17A	rs2275913 G>A	27
Arisawa et al[29]	2012	China	337	587	234/103	314/273	65.3 ± 11.4	61.4 ± 13.7	PCR-SSCP	IL-17A	rs2275913 G>A	33
Zeng et al[31]	2010	China	927	777	-	-	-	-	PCR-RFLP	IL-17F	rs763780 T>C	29
Shibata et al[20]	2009	Japan	287	524	203/84	307/217	65.0 ± 11.8	55.7 ± 18.3	PCR-SSCP	IL-17A	rs2275913 G>A	32
										IL-17F	rs763780 T>C

M: Male; F: Female; PCR-RFLP: Polymerase chain reaction-restriction fragment length polymorphism; PCR-SSCP: Polymerase chain reaction-single-strand conformation polymorphism; STROBE: Strengthening the Reporting of Observational Studies in Epidemiology.