Ascites and alpha-fetoprotein improve prognostic performance of Barcelona Clinic Liver Cancer staging

Table 3 Univariate analysis of baseline predictors of survival for each stage

Variable		BCLC A			BCLC B
		Number of patients	Median survival (mo)	P value	Number of patients	Median survival (mo)	P value
Age	< 56	250	39	0.590	259	19	0.230
	≥ 56	246	37		305	18
Sex	Male	414	37	0.550	452	18	0.080
	Female	82	39		112	23
Ascites	Absent	405	37	< 0.001	413	2014	< 0.001
	Present	91	22		151
Number of tumor nodules	One	404	37	0.003	0	-	-
	> 1	92	28		564	18
Maximum tumor diameter	≤ 5 cm	454	37	0.700	119	25	< 0.001
	> 5 cm	42	34		445	18
AFP (ng/mL)	< 200	330	37	< 0.001	322	20	< 0.001
	≥ 200	166	28		242	17
CTP class	A	268	39	< 0.001	261	24	< 0.001
	B	228	24		303	15

P-value < 0.05 is considered significant. AFP: Alpha-fetoprotein; BCLC: Barcelona Clinic Liver Cancer; CTP: Child-Turcott-Pugh score.