Prognostic role of neutrophil-lymphocyte ratio in operable esophageal squamous cell carcinoma

Table 3 Results of multivariable cox regression analysis

Prognostic factor	HR	95%CI	P value
CSS
Location (upper vs middle vs lower)	0.888	0.677-1.164	0.389
Differentiation (well vs moderate vs poor)	1.156	0.911-1.468	0.233
pT status ( T1 vs T2 vs T3)	1.101	0.778-1.559	0.586
pN status (N0 vs N1 vs N2 vs N3)	1.615	1.266-2.061	< 0.001
Stage (I vs II vs III)	1.460	0.907-2.351	0.120
NLR ( ≤ 3.0 vs > 3.0)	1.591	1.132-2.235	0.007
RFS
Differentiation (well vs moderate vs poor)	1.177	0.934-1.482	0.167
pT status (T1 vs T2 vs T3)	1.088	0.782-1.515	0.615
pN status (N0 vs N1 vs N2 vs N3)	1.703	1.337-2.169	< 0.001
Stage (I vs II vs III)	1.336	0.846-2.110	0.215
NLR ( ≤ 3.0 vs > 3.0)	1.525	1.094-2.126	0.013

NLR: Neutrophil-lymphocyte ratio; pN: Pathologic node; pT: Pathologic tumor; CSS: Cancer-specific survival; RFS: Recurrence-free survival.