Prognostic role of neutrophil-lymphocyte ratio in operable esophageal squamous cell carcinoma

Table 2 Univariate analysis of factors associated with recurrence-free survival and cancer-specific survival

Variable	Cases (n)	CSS (mo)			RFS (mo)
		Mean	Median	P value	Mean	Median	P value
Age (yr)				0.259			0.230
≤ 57.01	201	61.9	42		54.7	32
> 57.0	170	59.1	70		53.9	66
Sex				0.070			0.113
Female	95	72.2	NR		62.3	74
Male	276	59.5	45		52.8	34
Location				0.033			0.127
Upper	23	70.4	NR		52.2	58
Middle	256	52.7	41		48.8	35
Lower	92	74.8	NR		67.5	74
Differentiation				0.014			0.005
Well	58	55.0	55		52.1	58
Moderate	245	67.9	70		59.0	65
Poor	68	44.0	25		38.1	22
pT status				0.003			0.008
T1	17	60.5	NR		55.5	NR
T2	88	71.6	74		65.9	77
T3	266	59.4	39		51.1	29
pN status				< 0.001			< 0.001
N0	199	80.9	NR		71.7	87
N1	102	44.1	41		40.1	29
N2	55	25.0	15		21.2	10
N3	15	20.7	11		12.0	6
Stage				< 0.001			< 0.001
I	20	64.1	NR		62.6	NR
II	206	77.4	NR		68.3	85
III	145	32.7	21		29.0	15
NLR				< 0.001			0.001
≤ 3.0	297	68.3	70		61.0	58
> 3.0	74	41.2	24		38.3	17

¹Median age. CSS: Cancer-specific survival: NLR: Neutrophil-lymphocyte ratio; NR: Not reached; pN: Pathologic node; pT: Pathologic tumor; RFS: Recurrence-free survival.