Expression of pyruvate dehydrogenase is an independent prognostic marker in gastric cancer

Table 2 Relationship between pyruvate dehydrogenase expression and clinicopathological features of gastric carcinomas

Clinicopathologic variable	n	PDH expression
		-	+	PR (%)	P value1
	265	118	147	55.47
Sex					0.577
Female	71	34	37	52.11
Male	194	84	110	56.7
Age (yr)					0.902
< 60	133	60	73	54.89
≥ 60	132	58	74	56.06
Tumor size (cm)					0.347
< 4	80	32	48	60.00
≥ 4	185	87	98	52.97
Depth of invasion					0.093
Tis-1	25	7	18	72.00
T2-4	240	111	129	53.75
Lauren grade					0.001
Intestinal type	130	38	92	70.77
Diffuse type	135	81	54	40.00
TNM Stage					0.010
0-I	38	8	30	78.95
II-IV	227	110	117	51.54
Lymph node metastases					0.033
Negative	81	28	53	65.43
Positive	184	90	94	51.09
Lymphatic invasion					0.002
Absent	198	76	122	61.62
Present	67	41	26	38.81

¹Pearson χ² or Fisher’s exact test. PR: Positive rate; PDH: Pyruvate dehydrogenase.