Low contrast medium and radiation dose for hepatic computed tomography perfusion of rabbit VX2 tumor

Table 2 Quantitative image analysis (n = 11)

				P value
	80 kVp with IR	80 kVp	120 kVp	80 IR vs 120	80 vs 120
Normal liver
Arterial phase (HU)	78.88 ± 7.1	78.61 ± 7.27	71.57 ± 6.93	0.041	0.049
Portal venous phase (HU)	129.00 ± 5.70	129.5 ± 5.67	120.34 ± 5.26	0.002	0.001
Viable tumor
Arterial phase (HU)	131.68 ± 24.24	131.74 ± 24.29	122.15 ± 23.25	0.552	0.549
Portal venous phase (HU)	86.05 ± 12.82	87.77 ± 13.39	79.43 ± 10.59	0.357	0.211
Noise
NoiseHAP (HU)	9.31 ± 0.94	13.85 ± 1.05	8.16 ± 0.95	0.019	< 0.001
NoisePVP (HU)	9.50 ± 0.93	13.47 ± 1.27	8.27 ± 1.17	0.031	< 0.001
CNR
CNRHAP	5.63 ± 2.38	3.88 ± 1.82	6.16 ± 2.60	0.814	0.048
CNRPVP	4.60 ± 1.27	3.16 ± 1.04	5.11 ± 1.74	0.587	0.004

Data are expressed as mean ± SD. CNR: Tumor-to-liver contrast-to-noise ratio; IR: Iterative reconstruction.