Hepatitis B virus preS1 deletion is related to viral replication increase and disease progression

Figure 3 Quantification of deletion variants vs wild type virus by melting temperature height values in 72 cohort I subjects with deletions, according to their clinical statuses. The melting temperature height values of the deletion probe of each subject were normalized to the wild type probe. A: Comparison of the melting temperature height values between the subjects with hepatocellular carcinoma (HCC), liver cirrhosis (LC), and mild diseases [chronic hepatitis (CH) and carrier (C)]; B: Comparison of the melting temperature height values between subjects with severe diseases (HCC and LC) and mild disease (CH and C).