Irsogladine maleate and rabeprazole in non-erosive reflux disease: A double-blind, placebo-controlled study

doi:10.3748/wjg.v21.i16.5023

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Randomized Controlled Trial

World J Gastroenterol. Apr 28, 2015; 21(16): 5023-5031
Published online Apr 28, 2015. doi: 10.3748/wjg.v21.i16.5023

Table 1 Clinical features of patients receiving rabeprazole plus irsogladine maleate (group I) or rabeprazole plus placebo (group P)

	Group I (n = 49)	Group P (n = 48)	P value
Age (yr), mean ± SD	51.1 ± 16.4	51.1 ± 14.8	0.77
Sex, male/female	13/36	19/29	0.17
BMI (kg/m²)	22.4 ± 4.3	21.8 ± 3.1	0.59
Height (cm)	159 ± 7.3	161.5 ± 8.7	0.24
Weight (kg), mean ± SD	57.1 ± 12.2	56.7 ± 8.6	0.63
NERD grade (N/M)	21/28	20/28	0.91
Hiatal hernia (+/-)	11/38	10/38	0.85
Drinking (+/-)	16/33	20/28	0.36
Smoking (+/-)	2/47	9/39	0.05

NERD: Non-erosive reflux disease; BMI: Body mass index.

Citation: Suzuki T, Matsushima M, Masui A, Tsuda S, Imai J, Nakamura J, Tsukune Y, Uchida T, Yuhara H, Igarashi M, Koike J, Mine T. Irsogladine maleate and rabeprazole in non-erosive reflux disease: A double-blind, placebo-controlled study. World J Gastroenterol 2015; 21(16): 5023-5031
URL: https://www.wjgnet.com/1007-9327/full/v21/i16/5023.htm
DOI: https://dx.doi.org/10.3748/wjg.v21.i16.5023